Tensions in the Middle East soared on Friday as Israel launched a large-scale missile assault on Iranian military and nuclear installations, killing several senior Iranian officials and triggering a retaliatory barrage from Tehran.
Israeli Prime Minister Benjamin Netanyahu confirmed that the military operation targeting Iran’s facilities would continue “as many days” as deemed necessary, citing intelligence reports indicating that Iran was nearing the “point of no return” in its nuclear development.
The Iranian government swiftly denounced the Israeli offensive as a “declaration of war” and began launching its own attacks within hours. As missiles flew from both sides into the weekend, diplomatic warnings and appeals for calm echoed across the international community, which fears the confrontation could ignite a wider regional war.
Precision Attacks on Nuclear Facilities
The Israeli strikes began early Friday, a sacred day of rest and prayer in Iran. The offensive continued throughout the day, focusing on multiple targets, including the heavily fortified underground nuclear site at Natanz, which state television in Iran confirmed was struck multiple times. Despite the strikes, the head of the United Nations’ nuclear watchdog, Rafael Grossi, stated that external radiation levels remained stable.
Iran reported limited structural damage at its nuclear sites in Fordo and Isfahan but confirmed hits across several critical areas. The targeted attacks were calculated to disrupt Iran’s nuclear advancement while avoiding environmental catastrophe.
High-Ranking Casualties Among Iranian Forces
Among those killed in the air raids were senior figures within Iran’s military hierarchy. The head of the Islamic Revolutionary Guard Corps (IRGC), Hossein Salami, and Armed Forces Chief of Staff Mohammad Bagheri both died in the initial wave of airstrikes. Supreme Leader Ali Khamenei wasted no time in appointing successors.
Another major casualty was IRGC aerospace commander Amirali Hajizadeh, who oversaw Iran’s ballistic missile program. Iranian outlets also reported the deaths of multiple nuclear scientists, though specific identities were not disclosed. According to Iran’s ambassador to the United Nations, 78 people died and over 320 were wounded in the initial phase of the Israeli strikes.
Continued Assaults and Widespread Damage
Israeli forces expanded their campaign into Iran’s northwestern East Azerbaijan province, where 18 additional casualties were recorded, Iran’s IRNA news agency said. A spokesperson for the Israeli military disclosed that more than 200 targets were hit in total, including nuclear complexes and military airbases.
Though Prime Minister Netanyahu’s security adviser, Tzachi Hanegbi, emphasized that Israel had “no plan to kill” Iran’s top political leadership, speculation mounted regarding the scope and objectives of the campaign. Iran responded by restricting internet access nationwide, which the communications ministry said would be lifted once “normalcy returns.”
Iran’s Military Retaliation Unfolds
Iran’s Revolutionary Guard Corps confirmed it had launched dozens of missiles into Israel in retaliation, a statement matched by Israeli military reports that indicated most of the 100 drones sent in the first wave were intercepted outside Israeli borders. Nonetheless, early Saturday saw renewed missile strikes from Iran, with Israeli air raid sirens sounding across several regions.
The Israeli air force was reported to be actively intercepting new projectiles and neutralizing threats. Emergency medical teams treated 21 injured persons following a rocket impact along the Israeli coast, while 34 people sustained injuries in Gush Dan, a central metropolitan region. One woman died from wounds suffered in the latter strike, Israeli media reported.
The Role of the United States
Iran’s Foreign Minister Abbas Araghchi declared that Israel’s actions constituted “a declaration of war” and appealed to the United Nations Security Council for intervention. Iran had previously warned that any escalation could prompt it to strike U.S. military bases in the region. Preempting this, the United States evacuated non-essential personnel from several installations days before the Israeli strikes commenced.
President Donald Trump acknowledged that Israel had fully informed him ahead of the attack, but he asserted that the United States had not participated. Nevertheless, he issued a stern warning to Iran, stating that future assaults would be “even more brutal” and urging Tehran to return to nuclear negotiations “before there is nothing left.” Secretary of State Marco Rubio also cautioned Tehran against targeting American assets or personnel.
Iran’s Nuclear Program Under Scrutiny
While Iran continues to deny pursuing nuclear weapons, its uranium enrichment levels have reached 60 percent—well above the 3.67 percent limit set by the now-defunct 2015 nuclear accord but still shy of the 90 percent needed for weaponization. Diplomatic talks had been underway to address Iran’s nuclear trajectory, with another round scheduled in Oman for Sunday. That meeting has now been shelved amid the unfolding conflict.
Global Reactions and Rising Concerns
The ongoing hostilities have drawn widespread condemnation and appeals for de-escalation. Governments worldwide warned that further military escalation could destabilize the region, disrupt global oil supplies, and potentially involve other nations. United Nations Secretary-General António Guterres urged both sides to cease hostilities and pursue diplomatic solutions, stressing that “peace and diplomacy must prevail.”
Airspaces over Israel, Iran, Iraq, Jordan, and Syria were closed in response to the conflict. Numerous airlines suspended services in and out of the affected regions. Meanwhile, global oil prices surged briefly to around $75 per barrel before leveling off, as analysts warned of the immense risk posed to the Strait of Hormuz, through which 20 percent of the world’s crude oil passes.
The International Atomic Energy Agency announced plans to convene an emergency session on Monday to evaluate the impact of the hostilities on nuclear security in the region.
As the crisis deepens, the world watches anxiously, uncertain whether diplomatic channels can hold back a full-scale war in a region already brimming with volatility.
What you should know
The deadly Israeli missile strikes on Iranian nuclear and military sites mark one of the most dramatic escalations in Middle Eastern tensions in recent years. The death of top Iranian commanders and scientists, alongside Tehran’s retaliatory missile launches, has drawn global concern.
With regional airspaces closed, oil prices fluctuating, and peace talks suspended, the risk of a broader conflict grows, placing the entire region—and the global economy—on high alert.